Title Odos navikų fotodinaminė (fluorescencinė) diagnostika /
Translation of Title Photodynamic (fluorescence) diagnostics of skin lesions.
Authors Liutkevičiūtė Navickienė, Jurgita
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Pages 107
Keywords [eng] photodynamic diagnostics ; skin lesions ; fluorescence
Abstract [eng] The diagnostic value and methodological features of photodynamic (fluorescence) diagnostics in skin lesions were analysed during the study. In addition, fluorescence induced by different photosensitizer precursors (5-aminolevulinic acid and methyl aminolevulinate) was compared. The possibilities of photodynamic diagnostics in skin lesions using light sources with different wavelength were investigated in this study. The optimal wavelength of light for inducing fluorescence in skin lesions was determined in order to diagnose tumours of different histological types (i.e. squamous cell carcinoma, basal cell carcinoma and premalignant lesions). The differences of fluorescence in malignant and premalignant skin lesions were evaluated. Photodynamic diagnostics furthermore was used as method of visualisation helping to delineate exact margins of skin tumour before and during the treatment and to achieve thoroughness of treatment in patients with malignant epithelial skin tumours.
Type Doctoral thesis
Language Lithuanian
Publication date 2010