| Title |
NMR spectroscopy of structure, diffusion and relaxation in materials used in innovative medicine |
| Translation of Title |
Struktūros, difuzijos ir relaksacijos vyksmų medžiagose, taikomose inovatyvioje medicinoje, BMR spektroskopija. |
| Authors |
Kristinaitytė, Kristina |
| ISBN |
9786090702383 |
| Full Text |
|
| Pages |
168 |
| Keywords [eng] |
NMR spectroscopy ; prostate MRS ; Gd-based UCNP ; lyotropic chromonic liquid crystal ; calcium hydroxyapatite |
| Abstract [eng] |
Fast development of explicit and novel applications of nanomaterials in nearly all domains is undeniable. The versatility of NMR brought an array of applications addressing potential future developments of nano-structure materials and NMR-based methods applied in clinical routine. In this dissertation four fields demonstrating the utility of NMR were covered: magnetic resonance spectroscopy (MRS) of metabolites present in prostate; up-converting nanoparticles (UCNPs) as potential multimodal MRI contrast agents (CAs); sunset yellow (SSY) as a lyotropic chromonic liquid crystal (LCLC) which promises a new generation of medical diagnostic tools - small and portable biosensors; and calcium hydroxyapatite (CaHA) as novel nano-structured materials that can be used for the treatment of bone defects. The first two groups of materials can be directly applied in NMR-based imaging modalities as potential cancer biomarkers. The second two correspond to innovative materials that can be utilized in medicine and NMR spectroscopy is a useful tool for their analysis. |
| Dissertation Institution |
Vilniaus universitetas. |
| Type |
Doctoral thesis |
| Language |
English |
| Publication date |
2019 |
